You are now
leaving this site

If you'd like to stay, click "CANCEL."
Cancel Continue

Are you a healthcare provider (HCP)?

This link will take you to a website that was specifically created for HCPs in the US.
Continue to HCP site Stay here

Title

Description

Caption

Purple Backgrounded Box

Blank

Joenja
(n/N=18/21)

Placebo
(n/N=8/10)

Baseline mean (SD)

3.03 (0.42)

3.05 (0.39)

Change from baseline, LS mean (SE)

-0.27 (0.04)

-0.02 (0.05)

Difference vs placebo (95% CI)

-0.25 (-0.38,-0.12)

APDS Assist is here to help you every step of your Joenja journey.

Explore the resources and support available to you throughout your treatment to help you start and stay on Joenja.

Explore APDS Assist

→

Patient brochure

Get helpful tips and reminders for taking Joenja.


Download brochure

Patient brochure

Get helpful tips and reminders for taking Joenja.


Download guide

→

Patient brochure

Get helpful tips and reminders for taking Joenja.


Download form

→

Connect with a Care Coordinator at APDS Assist

Call 1-877-796-APDS (2737)

8 am-8 PM ET, Monday-Friday

APDS Assist Care Coordinators are here to help you navigate coverage, access, and financial support options when you are prescribed Joenja. They are also able to connect you with your ACE

APDS, activated PI3K delta syndrome.

See how Joenja works to manage APDS

→

See how Joenja works to manage APDS

→

Slab 36px White

Slab 36px Dark Purple

Slab 26px Dark Purple

Flex 26px Dark Purple

Slab 20px Dark Purple

Flex 22px Black

Flex 18px Black

Flex 18px Purple Bold

Flex 18px Black

Flex 16px White

Bunch of text

Expand

Approved Use

JOENJA® (leniolisib) is a prescription medicine that is used to treat activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS) in adults and children 12 years of age and older.

Important Safety Information

Tell your healthcare provider if you are pregnant or plan to become pregnant. JOENJA may harm your unborn baby. Your healthcare provider will do a pregnancy test before you start receiving JOENJA.

Approved Use

JOENJA® (leniolisib) is a prescription medicine that is used to treat activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS) in adults and children 12 years of age and older.

Important Safety Information

Tell your healthcare provider if you are pregnant or plan to become pregnant. JOENJA may harm your unborn baby. Your healthcare provider will do a pregnancy test before you start receiving JOENJA.

Use effective birth control to prevent pregnancy while taking JOENJA and for one week after you stop taking JOENJA. If you plan to become pregnant, continue taking your birth control for one week after stopping JOENJA. Talk to your doctor about what type of birth control method is right for you while taking JOENJA.

It is not known if JOENJA passes into your breast milk. Talk to your doctor about the best way to feed your baby if you take JOENJA.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. JOENJA and certain other medicines may affect each other.

Tell your healthcare provider if you are scheduled to receive an immunization (vaccine). JOENJA may affect how well a vaccine works.

Know the medicines you take. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine.

The most common side effects of JOENJA include headache, inflammation of sinuses, and dry, itchy, and inflamed skin (eczema). These are not all the possible side effects of JOENJA. Tell your healthcare provider about any side effect that bothers you or does not go away.

You can also report negative side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch, or Pharming Medical Affairs at (800) 930-5221.

For more information, please see the full Prescribing Information.

Expand

USO APROBADO

JOENJA® (leniolisib) is a prescription medicine that is used to treat activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS) in adults and children 12 years of age and older.

INFORMACION DE SEGURIDAD IMPORTANTE

Informe a su proveedor de atención médica si está embarazada o planea quedar embarazada. JOENJA puede hacerle daño a el feto. Su proveedor de atención médica le hará una prueba de embarazo antes de que empiece a recibir JOENJA.

USO APROBADO

JOENJA® (leniolisib) es un medicamento de venta con receta médica que se utiliza para tratar el síndrome de fosfoinositida 3-cinasa delta activada (PI3Kδ) en adultos y niños mayores de 12 años.

INFORMACION DE SEGURIDAD IMPORTANTE

Informe a su proveedor de atención médica si está embarazada o planea quedar embarazada. JOENJA puede hacerle daño a el feto. Su proveedor de atención médica le hará una prueba de embarazo antes de que empiece a recibir JOENJA.

Utilice un método anticonceptivo eficaz para prevenir el embarazo mientras esté tomando JOENJA y durante una semana después de dejar de tomar JOENJA. Si planea quedar embarazada, continue tomando su método anticonceptivo durante una semana después de dejar de tomar JOENJA. Hable con su médico sobre qué tipo de método anticonceptivo es adecuado para usted mientras toma JOENJA.

Se desconoce si JOENJA pasa a la leche materna. Hable con su médico sobre la mejor manera de alimentar a su bebé si toma JOENJA.

Dígale a su médico todos los medicamentos que esté tomando, incluso los adquiridos con o sin receta, vitaminas y suplementos a base de hierbas. JOENJA y ciertos medicamentos pueden afectarse entre sí.

Informe a su médico si tiene programada una inmunización (vacuna). JOENJA puede afectar la eficacia de una vacuna.

Conozca los medicamentos que toma. Lleve una lista de sus medicamentos y enséñesela a su proveedor de atención médica y a su farmacéutico cuando adquiera un medicamento nuevo.

Los efectos secundarios más frecuentes de JOENJA incluyen dolor de cabeza, inflamación de los senos paranasales y sequedad, y picor e inflamación de la piel (eczema). Estos no son todos los posibles efectos secundarios de JOENJA. Informe a su médico de cualquier efecto secundario que le moleste o que no desaparezca.

También puede informar sobre los efectos secundarios negativos a la FDA en el 1-800-FDA-1088 o www.fda.gov/medwatch, o a Pharming Medical Affairs en el (800) 930-5221.

Para más información, consulte la Información de prescripción completa.

About APDS

What Is APDS? Diagnosing APDS

What Is Joenja?

How Joenja Works Joenja Results

Taking Joenja

Taking Joenja

Real Patient Stories

Real Patient Stories

Resources & Support

APDS Assist Resources Recursos (Español)

Get in touch

Get in touch
Full Prescribing Information Contact Us Privacy Policy Terms of Use Cookie Policy
Joenja and logo are registered trademarks of Pharming Intellectual Property, B.V.
© 2025 Pharming Healthcare, Inc. All rights reserved.
JOE-US-2023-0009v10

Privacy settings

Decide which cookies you want to allow.

You can change these settings at any time. However, this can result in some functions no longer being available. For information on deleting the cookies, please consult your browser’s help function.

Learn more about the cookies we use.

With the slider, you can enable or disable different types of cookies:

  • Block all
  • Essentials
  • Functionality
  • Analytics
  • Advertising

This website will:

This website won't:

  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Keep track of what you input in a shopping cart
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settings
  • Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track of the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Tailor information and advertising to your interests based on e.g. the content you have visited before. (Currently we do not use targeting or targeting cookies.
  • Advertising: Gather personally identifiable information such as name and location
  • Remember your login details
  • Essential: Remember your cookie permission setting
  • Essential: Allow session cookies
  • Essential: Gather information you input into a contact forms, newsletter and other forms across all pages
  • Essential: Keep track of what you input in a shopping cart
  • Essential: Authenticate that you are logged into your user account
  • Essential: Remember language version you selected
  • Functionality: Remember social media settings
  • Functionality: Remember selected region and country
  • Analytics: Keep track of your visited pages and interaction taken
  • Analytics: Keep track about your location and region based on your IP number
  • Analytics: Keep track of the time spent on each page
  • Analytics: Increase the data quality of the statistics functions
  • Advertising: Tailor information and advertising to your interests based on e.g. the content you have visited before. (Currently we do not use targeting or targeting cookies.
  • Advertising: Gather personally identifiable information such as name and location
Save & Close